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|| Mira Petrovic, Institució Catalana de Recerka e Estudis Avançants (ICREA), Barcelona, Spain
||Faculty of Chemical Engineering and Technology, Marulicev trg 19, 10000 Zagreb;
http://www.fkit.hr; contact person: Prof. Antun Glasnovic, dean of Faculty, tel.
3851-4597-281, e-mail: email@example.com
||Veterina, Animal Health, Kalinovica, Hrvatska
||Reduction of environmental risks posed by pharmaceuticals and their degradation products in process wastewaters, through RO/NF membrane treatment (REPHAD)
||In Croatia, industrial and agriculture wastewaters are mainly discharged untreated
to the rivers. Thus, the future of indirect potable reuse requires a planned
protection of surface waters through efficient treatment of wastewaters prior to their
discharge and the occurrence of contaminants is a key issue in relation to the
quality of water supplies.
Project REPHAD addresses the so-called “emerging” or “new” contaminants, particularly
human and veterinary pharmaceuticals, whose emission has recently emerged as an
environmental problem. It focuses on their tracing in industrial and agriculturall effluents and
on their removal by advanced membrane (RO/NF) technologies. Emphasis is on the
application of small units for the treatment of effluents with the objective to reduce
environmental and health risks due to improvement of the quality of receiving surface waters.
In this project a highly selective and high throughput chromatographic methods for
simultaneous determination of pharmaceutical and their degradation products in highly
complex wastewater matrices will be developed. The method involves sample pre-treatment
by solid-phase extraction (SPE) and analytical determination by high performance liquid
chromatography (HPLC) coupled with DAD, FLD and MS detectors.
The project also aims to achieve an improved understanding of the biotransformation and
ecotoxicity of emerging contaminants in the environment and during water treatment applying
advanced analytical methods based on Toxicity Identification Evaluation (TIE) approach.
The fact that these compounds are not in the regulatory list of environmental pollutants
resulted in comparatively little attention paid to them. Although pharmaceuticals are expected
to occur in trace concentrations, because of their continuous use and bacterial resistance
attributed to their action, they represent particular problem. Their incomplete removal from the
wastewater treatment plants (WWTPs) is referred to as the major source of their release into
environment. Therefore, multiresidue analytical method is a prerequisite to provide reliable
data on the behavior of pharmaceuticals in WWTPs. The information obtained from analysis of
influents and effluents of WWTPs may serve to optimize a treatment process or possible pretreatmentstep so that the emission of undesired pollutants into the receiving waters is
The scientific and technological objectives are focused on the investigation of wastewater
treatment technologies at laboratory and pilot scale.
||U Hrvatskoj se industrijske i poljoprivredne otpadne vode u većini slučajeva neobrađene ispuštaju u vodotokove. U projektu se obrađuje ekološki problem uslijed sve veće količine tzv. novih zagađivala, posebice humanih i veterinarskih lijekova u vodama. Istraživat će se njihova prisutnost u industrijskim i poljoprivrednim otpadnim vodama i njihovo uklanjanje naprednim membranskim tehnologijama temeljenim na reverznoj osmozi i nanofiltraciji. Naglasak je na manjim uređajima za obradbu otpadnih voda kojima će se poboljšati kvaliteta prihvatnih vodotokova i tako smanjiti rizik po okoliš i ljudsko zdravlje. S tim ciljem razvit će se vrlo selektivne kromatografske metode kojima će se u složenim uzorcima otpadnih voda moći istovremeno odrediti velik broj farmaceutika i njihovih razgradnih produkata. Unaprijedit će se i spoznaje o ekotoksičnosti i mogućim biološkim promjenama faramaceutika u okolišu i tijekom postupka obradbe otpadnih voda
|Amount requested from UKF:
||200 000 €
|Amount of matching funding:
||40 000 €